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KMID : 0357920140480060423
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Korean Journal of Pathology
2014 Volume.48 No. 6 p.423 ~ p.425
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Primary Leiomyosarcoma of Adrenal Gland with Tissue Eosinophilic Infiltration
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Lee Seung-Koo
Tanawit Gail Domecq C.
Lopez Rolando A.
Zamuco Jaime T.
Cheng Betsy Grace G.
Siozon Menandro V.
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Abstract
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Eosinophils are associated with numerous disorders, including helminthic parasitic infections, allergic diseases, and some tumors.1 Although eosinophils are commonly encountered in human solid tumors, their functional role in neoplasm remains a matter of controversy.1 The correlation of tumor-associated tissue eosinophilia (TATE) with prognosis has shown variable results in several malignancies.1-4 Primary adrenal leiomyosarcoma is a very rare malignant mesenchymal tumor with smooth muscle differentiation. Twenty-two cases have been reported in the English5,6 and Korean7 literature. The association of tissue eosinophilia with leiomyosarcoma is very rare, with only one
case of uterine leiomyosarcoma reported in the literature.4 We experienced a very rare case of primary adrenal leiomyosarcoma with marked tissue eosinophilia, it is the first case reported in the literature.
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